DNA methylation plays a critical role in developmental and physiological processes, where aberrant methylation can lead to a variety of disease states including cancer. Cell-free DNA (cfDNA) samples ...
The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.
In recent years, the study of epigenetics and its role in disease has increased dramatically. DNA methylation, which influences the ability of proteins to bind the DNA and thereby regulates gene ...
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